A series of misfortunes leaves the Knick facing a state of upheaval in Season 2 of Steven Soderbergh's Emmy®-nominated series. With Thackery (Clive Owen) away to treat his cocaine addiction, a dearth of affluent patients and financial missteps plaguing the NYC hospital, the board decides to relocate uptown. Meanwhile, gifted black surgeon Algernon Edwards (Andre Holland) jockeys to become Thackery's successor as Chief of Surgery as the rest of the staff grapples with numerous challenges, both at work and in their private lives.