The Department of Puberty

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Andrew Rannells

Matthew (voice)

Bobby Cannavale

Gavin the Hormone Monster (voice)

Neil Casey

Detective Dumont / D.N. Ape (voice)

Jessica Chaffin

Shannon Glaser / Grace / Intellect Sphinx (voice)

Kat Dennings

Leah Birch / Lorraine the Hormone Monstress (voice)

John Gemberling

Tyler the Hormone Monster (voice)

Joe Wengert

Stan the Hormone Monster / Ambition Gremlin (voice)

Natasha Lyonne

Suzette (voice)

Gil Ozeri

Brad (voice)

David Thewlis

Shame Wizard (voice)

Nathan Fillion

Nathan Fillion (voice)

Jon Daly

Judd Birch (voice)

Jean Smart

Depression Kitty (voice)