Florida

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Andrew Rannells

Matthew MacDell (voice)

Maya Rudolph

Diane Birch / Constance the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Jessica Chaffin

Shannon Glaser (voice)

David Cross

Skip Glouberman (voice)

Carol Kane

Menopause Banshee / Old Woman (voice)

Mark Rivers

Maury's Backup Singer (voice)

Emily Altman

Vicky (voice)

Julie Klausner

Cherry Marashina (voice)

Paula Pell

Barbara Glouberman (voice)

Richard Kind

Marty Glouberman (voice)

Judd Hirsch

Lewis Glouberman (voice)