The Shane Lizard Rises

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jenny Slate

Missy Foreman-Greenwald (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Andrew Rannells

Matthew MacDell (voice)

Maya Rudolph

Diane Birch / Constance the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Brandon Kyle Goodman

Walter the Lovebug (voice)

Pamela Adlon

Sonya the Lovebug (voice)

Ayo Edebiri

Missy Foreman-Greenwald (voice)

Fran Gillespie

Samira (voice)

Jak Knight

DeVon

Jack McBrayer

Pubic Hair #1 (voice)

Seth Morris

Greg Glaser (voice)

Richard Kind

Marty Glouberman (voice)

Chloe Fineman

Leah Birch (voice)