Sex-Change?

Sex-change frequently makes press headlines along with confusing reports of the physiology involved. The withdrawal of five gold-medal-winning women athletes from this year's European Championships, supposedly to avoid the recently introduced ' sex checks,' has raised the question again.
What does ' sex-change ' mean?
Does it, in fact, happen? In one of tonight's items Horizon looks at this complex psychological and physiological subject.

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S1966E23 - The Structure of Life