Horny Talky Yes Please

Nick Kroll

Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)

John Mulaney

Andrew Glouberman (voice)

Jessi Klein

Jessi Glaser (voice)

Jason Mantzoukas

Jay Bilzerian (voice)

Maya Rudolph

Diane Birch / Connie the Hormone Monstress (voice)

Fred Armisen

Elliot Birch (voice)

Jordan Peele

Ghost of Duke Ellington (voice)

Mark Duplass

Andrew Rannells

Paul Scheer

Thandiwe Newton

Mark Rivers

Whitmer Thomas

Joe Wengert

Nathan Fillion

Chloe Fineman

Natasha Lyonne

Ms. Dunn (voice)

Crissy Guerrero

Gil Ozeri

Neil Casey

Heather Lawless

Keke Palmer