Why is Breast Milk Special (Making Better Formula)

Why don’t we have baby formula that’s just as good as breast milk? Sam chats with chemist Dr. Steven Townsend, who’s trying to figure out which sugar molecules in breast milk make it so unique and difficult to recreate in the lab. #breastmilk #babyformula #formula #milk

For more about Dr. Townsend and his research, check out his C&EN Talented 12 profile: https://cen.acs.org/biological-chemistry/natural-products/Steven-D-Townsend/97/i33

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Credits:
Executive Producers:
George Zaidan
Hilary Hudson

Producers:
Andrew Sobey
Elaine Seward

Writer/Host:
Samantha Jones, PhD

Scientific consultants:
Lelia Duman, PhD
Brianne Raccor, PhD
Steven D. Townsend, PhD

Sources:
Effects of Infant Formula With Human Milk Oligosaccharides on Growth and Morbidity: A Randomized Multicenter Trial
https://pubmed.ncbi.nlm.nih.gov/28107288/

A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations that Result in Potentiation of Trimethoprim.
https://mbio.asm.org/content/11/2/e00076-20?rss=1

Interrogation of Human Milk Oligosaccharide Fucosylation Patterns for Structural Antimicrobial and Antibiofilm Trends in Group B Streptococcus.
https://pubs.acs.org/doi/10.1021/acsinfecdis.8b00234

Lacto-N-Tetraose Exhibit Antimicrobial Activity Against Group B Streptococcus.
https://pubs.rsc.org/en/content/articlelanding/2014/OB/C8OB02080A#!divAbstract

Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides Against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii.
https://pubs.acs.org/doi/10.1021/acsinfecdis.7b00183

The Human Milk Glycome as a Defense Against Infectious Diseases
https://pubs.acs.org/doi/10.1021/acsinfecdis.7b00209

Human Milk Oligosaccharides Exhibit Antimicrobial and Anti-Biofilm Properties Against Group B Streptococcus.
https://pubs.acs.org/doi/10.1021/acsinfecdis.7b00064

Steven D. Townsend: Oligosaccharide explorer is solving the mysteries of breast milk sugars https://cen.acs.org/biological-chemistry/natural-products/Steven-D-Townsend/97/i33

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