Royal Scam

Neil Patrick Harris

Peter Parker / Spider-Man (voice)

Lisa Loeb

Mary Jane Watson (voice)

Ian Ziering

Harry Osborn (voice)

Angelle Brooks

Indira "Indy" Daimonji (voice)

SuChin Pak

Alison Tomita (voice)

Keith Carradine

J. Jonah Jameson

Michael Dorn

Kraven the Hunter

Virginia Madsen

Silver Sable

Rob Zombie

Dr. Curt Connors / the Lizard

Cree Summer

Professor Williams / Jolenna

Jennifer Hale

Female Reporter / Female News Announcer

Stan Lee

Frank Elson

Clancy Brown

Raymond (voice)

Michael Clarke Duncan

Wilson Fisk / The Kingpin (voice)

Gina Gershon

Shikata (voice)

John C. McGinley

Richard Damien (voice)

Karen Maruyama

Shadowy Woman / Flower Vendor (voice)

Keith David

Agent Mosely (voice)