Eastbound & Down

Danny McBride

Kenny Powers

Steve Little

Stevie Janowski

Katy Mixon

April Buchanon

John Hawkes

Dustin Powers

Jennifer Irwin

Cassie Powers

Elizabeth De Razzo

Maria

Bo Mitchell

Wayne

Ethan Alexander McGee

Dustin Jr.

Jillian Bell

Dixie

Tim Heidecker

Gene

Ken Marino

Guy Young

Michael Beasley

Jimmy Clay

Mariano Mendoza

Rodney 'Hammer' Garcia

Ana de la Reguera

Vida

Ike Barinholtz

Ivan Dochenko

Efren Ramirez

Catuey

Marco Rodríguez

Roger Hernandez

Jason Sudeikis

Cole Gerald / Shane Gerald / Shane Gerald / Cole Gerald

John Cothran

Baseball Coach

Justin Miles

Jacques

Eddie 'Piolin' Sotelo

Announcer

Michael Peña

Mr. Cisneros

Sylvia Jefferies

Tracy

Will Ferrell

Ashley Schaeffer

Don Johnson

Eduardo Sanchez

Alex ter Avest

Andrea

Andy Daly

Terrence Cutler

Craig Robinson

Reg Mackworthy

Erick Chavarria

Casper

Amber Brooke

Kate

Jerry Minor

Jamie Laing

Omar J. Dorsey

Dontel Benjamin

Jon Reep

Jed Forney

Joaquín Cosío

Hector

Deep Roy

Aaron

Matthew McConaughey

Roy McDaniel

Lily Tomlin

Tammy Powers

Ben Best

Clegg

Adam Scott

Pat Anderson

Alisa Harris

Brenda

Diva Tyler

Mamie

Rhoda Griffis

The Teacher

Raiko Bowman

Woman On Boardwalk

Chandler Massey

Pliny Caldwell

Simon Rhee

Sensei

Marlene Forte

Soledad

Jody Hill

Andrew, Pat Anderson's Sponsor

Joe Buck

Joe Buck

Gina Gershon

Realtor

Shannon Eubanks

Donna Schaeffer

Jill Jane Clements

Shane's Mom

Megan Hayes

Gloria

Tim Ware

Shane's Dad

Robin Mullins

Bobbi

Seth Rogen

Texas Pitcher

Mandi Beers

Dottie

Cat Cora

Self

Marilyn Manson

Roller Rink Server

Samantha Beaulieu

Candy Cox

Sacha Baron Cohen

Ronnie Thelman

Alexander Skarsgård

Adult Toby Powers

Lindsay Lohan

Adult Shayna Powers