A temporada 4 de Operation Ouch! foi transmitida em CBBC de lundi 18 janvier 2016 a lundi 14 mars 2016. Consiste em 9 episódios, o primeiro se chama "How Your Nerves Work" e o último "Best Of..."..
Operation Ouch! is a British children's educational television series about the human body. It shows what happens in A&E, what doctors sometimes have problems with and great experiments. The show is hosted by twin brothers Dr Chris and Dr Xand van Tulleken. Series 5 was named "Operation Ouch! Hospital Takeover".