After a century of sleep, Dracula awakens in the Transylvanian Alps and spreads a glowing powder that turns people into vampires. Batman and Robin are captured at his castle, and Wonder Woman and Aquaman battle swarms of victims. In Vienna, Superman confronts Dracula and is transformed. As the plague spreads, the remaining heroes regroup in Switzerland and seek a rare South American bat in the Andes whose cave gases may cure the curse and stop Dracula.