Seis Manos

Aislinn Derbez

Isabela (voice)

Mike Colter

Wallace Brister (voice)

Jonny Cruz

Jesus (voice)

Angélica Vale

Garcia (voice)

Vic Chao

Chiu / Lo (voice)

Danny Trejo

Baldemar / El Balde (voice)

Carlos Luna

Domingo (voice)

Raúl Castillo

(voice) / Nachito (voice) / Nachito / State Police Captain (voice)

Christian Lanz

(voice) / Jaimito (voice) / Von / Man on TV (voice)

Eric Lopez

(voice)

Rose Portillo

(voice)

Philip Anthony-Rodriguez

(voice) / Melo (voice)

Fryda Wolff

(voice)

Luisa Leschin

(voice)

Roger Craig Smith

Larry (voice)

Nika Futterman

Young Isabela (voice)

Tony Amendola

Padre Serrano (voice)

Carl Thiel

Newscaster (voice)

Jewels Jaselle

Brigida / Brigida's Brother