La saison 4 de Live at the Apollo a été diffusée sur BBC Two du vendredi 28 novembre 2008 au vendredi 16 janvier 2009. Elle comporte 6 épisodes, le premier s'intitule "Michael McIntyre, Rich Hall, Rhod Gilbert" et le dernier "Russell Howard, Jo Brand".
At the forefront of its genre, the roll-call of stand-ups who have performed in front of the famous Live At The Apollo lights plays out like a who's who of comedic royalty. Each episode sees a national (and sometimes international) stand-up both compering and performing, before introducing two of the best established and up-coming stand-ups to the stage.