Nicole Sullivan

Janet Novak

JJ

Jen Caulder

Teacher

Jill Tracy

Joanne DeMarco

(voice) / Alexis Radcliffe (voice) / Amber (voice) / Angelica / Cheerleader / Sorority Girl (voice) / Boxer (voice) / Bride / Candi / Mary (voice) / Drunk Chick (voice) / Girl in a Scavenger Hunt / Cashier (voice) / Joan the Maid (voice) / Mega Hardware Customer (voice) / Meredith (voice) / Mrs. Abbott (voice) / Mrs. Goldman (voice) / Muriel Goldman (voice) / Nurse at Sperm Bank (voice) / Shelly / Muriel Goldman (voice) / Stewie's Customer (voice) / Taco Lover (voice) / Tina (voice)

Nancy Twicker

(voice) / Fan Girl (voice) / Party Goer (voice)

Vicki

Janice (voice)

Self - Judge

Mrs. Cobblepot / Benjamin (voice)

Janine

Robin

Teresa

Alexis

Carol / Carol Salazar-Roberts

Bea Greer

Leanne

Heather Moscone

Miss Klotz

Shego (voice) / Shego / Computer Voice (voice) / Shego / Miss Go (voice)

Supergirl (voice)

Lorraine

Shego (voice)

Debbie / Customer (voice)

Joan of Arc (voice)

Pam

Alicia

Joan Rubin

Maria

Holly Shumpert / Marilyn

Marlene (voice)

Self

Nurse

Kreuftlva

Kara Danvers / Supergirl (voice)

Carolyn Crumley

Melanie

Princess Mira Nova (voice)

Lida / Meg Ryan / Mindy Tikvah / Self / Various

Gerri (voice)

Joan of Arc (voice)

Young Woman

Bonnie Goodson

Diane Pulaski

Self

Tundra Woman (voice)

Wilma Bassett

Julia Riker

Franny (voice)

Liz Klein

Ant #9 (voice)

Mira Nova (voice)

Lyla

Patricia Nixon

Supergirl (voice)

Marlene

Shego (voice)

Ms. James

Supergirl (voice)

Ellen

Kara Zor-El/Supergirl (voice)

Shego (voice)

Marlene (voice)

Bizzy (voice)

Maureen

Dr. Pytel (voice)

Randi

Alissa